LD score comparisons between gnomAD and UK Biobank
In this analysis, we aimed to better understand the similarities and differences between imputation-based and sequence-based LD scores. To this end, we compared LD scores from gnomAD (sequence-based) and UKB (imputation-based) across four ancestry groups: African (AFR), Admixed American (AMR), East Asian (EAS), and North-Western European (EUR; NWE in gnomAD). This also serves as a more general comparison between LD scores from two separate cohorts. LD scores were obtained as follows.